Kyler Murray and the Arizona Cardinals (2-3) couldn’t get a game-tying field goal in Week 5 and now limp into a road game against Geno Smith’s Seattle Seahawks (2-3) in a game with huge NFC West implications.
Can Kliff Kingsbury’s Cardinals get a road win, or will Seattle’s Smith, who leads the NFL in quarterback rating, keep throwing it en route to a Week 6 win over Arizona? The game is scheduled to begin on Sunday at 4 pm ET from CenturyLink Field.
Here’s a look at USA TODAY’s NFL staff betting details and picks for the Cardinals’ Week 6 game against the Seahawks:
Cardinals at Seahawks odds, safe and over/under
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NFL Week 6 odds, predictions and picks
Commanders vs Bears | Patriots vs. Browns | Pirates vs. Steelers | Ravens vs Giants | Vikings vs. Dolphins | Jets vs Packers | 49ers vs. Falcons | Bengal vs. Saints | Jaguars vs. Colts | Cardinals vs. Seahawks | Panthers vs. Rams | Bills against principals | Cowboys vs. Eagles | Broncos vs. Chargers
Lorenzo Reyes: Seahawks 33, Cardinals 27
Seattle has a surprisingly explosive offense and Geno Smith is one of the more efficient passers in the league right now. The Cardinals are still sorely missing DeAndre Hopkins, who is eligible to return after this week. Until then I’m keeping Arizona.
Safid Deen: Seahawks 24, Cardinals 21
Kyler Murray’s late mistake cost the Cardinals in their attempt to beat the undefeated Eagles last week. But give me Geno Smith and the pesky Seahawks in their first home game in two weeks.
Lance Pugmire: Cardinals 27, Seahawks 24
A major injury loss of running back Rashaad Penny puts more pressure on a revived Geno Smith, meaning a likely air show aimed at DK Metcalf sand Tyler Lockett as Arizona appreciates the buzzer break from home, where it has lost eight straight.
Jarrett Bell: Seahawks 24, Cardinals 23
Nate Davis: Cardinals 27, Seahawks 24
Tyler Dragon: Cardinals 24, Seahawks 20
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